Pressurized hot water extraction of 10-deacetylbaccatin III from yew for industrial application
نویسندگان
چکیده
منابع مشابه
Pressurized hot water extraction (PHWE).
Pressurized hot water extraction (PHWE) has become a popular green extraction method for different classes of compounds present in numerous kinds of matrices such as environmental, food and botanical samples. PHWE is also used in sample preparation to extract organic contaminants from foodstuff for food safety analysis and soils/sediments for environmental monitoring purposes. The main paramete...
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Carotenoids are known for their antioxidant activity and health promoting effects. One of the richest sources of carotenoids are carrots. However, about 25% of the annual production is regarded as by-products due to strict market policies. The aim of this study was to extract carotenoids from those by-products. Conventional carotenoid extraction methods require the use of organic solvents, whic...
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298 Introduction Environmental and biological analyses are especially challenging for the analyst because sample matrices tend to be very complex and the analytes are present at very low levels. Selective and sensitive methods are needed for both sample preparation and analysis. Typically, extraction and clean-up are needed in the sample preparation, and the analyses are performed by chromatogr...
متن کاملImproving 10-deacetylbaccatin III-10-β-O-acetyltransferase catalytic fitness for Taxol production
The natural concentration of the anticancer drug Taxol is about 0.02% in yew trees, whereas that of its analogue 7-β-xylosyl-10-deacetyltaxol is up to 0.5%. While this compound is not an intermediate in Taxol biosynthetic route, it can be converted into Taxol by de-glycosylation and acetylation. Here, we improve the catalytic efficiency of 10-deacetylbaccatin III-10-O-acetyltransferase (DBAT) o...
متن کاملOptimization of pressurized hot water extraction of Lavandin essential oils via central composite design
Pressurized hot water extraction (PHWE) and hydrodistillation were compared for the extraction of essential oil from Lavandin. Using GC-FID analysis in conjunction with central composite design, the maximum extraction yield was obtained for temperature of 148 o C, pressure of 33.7 (bar), static time of 10.7 (min), dynamic time of 17.6 (min), and flow rate of 0.69 (mL/min). The PHWE is a practic...
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ژورنال
عنوان ژورنال: Resource-Efficient Technologies
سال: 2017
ISSN: 2405-6537
DOI: 10.1016/j.reffit.2017.03.007